Human DEFB1 Protein, hFc Tag
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Product Number
KMP3188
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Alias
防御素β1, Human DEFB1 Protein, hFc Tag, DEFB1
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Specifications
- 50ug
- 100ug
- 200ug
Product Description
| Alias | 防御素β1, Human DEFB1 Protein, hFc Tag, DEFB1 |
| Catalog Number | KMP3188 |
| Product Description | The Human DEFB1 Protein(KMP3188) is produced in HEK293 Cells. The target gene encoding the human DEFB1 (NP_005209.1) (Met1-Lys68) is expressed with the Fc region of human IgG1 at the C-terminus. |
| Molecular Name | DEFB1 |
| Species | Human |
| Host | HEK293 Cells |
| Size | 50ug, 100ug, 200ug |
| Purity | >95% as determined by SDS-PAGE |
| Purification | Affinity purification |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Formulation | PBS, pH7.4 |
| Background | The DEFB1 gene, encoding for the constitutively expressed human beta-defensin 1 (hBD1) antimicrobial peptide is a potential candidate when studying genetic susceptibility to caries. DEFB1 genetic variations have been reported as contributing to hBD1 production impairment, leading to a greater susceptibility to be infected by oral pathogens, also leading to periodontitis. To counteract host immunity, Cryptosporidium parvum has evolved multiple strategies to suppress host antimicrobial defense. One such strategy is to reduce the production of the antimicrobial peptide beta-defensin 1 (DEFB1) by host epithelial cells. Beta-Defensin-1, an antimicrobial peptide encoded by the DEFB1 gene, is known to play an important role in lung mucosal immunity. |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
| Molecular Weight | 31.8 kDa |
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