Human PRND Protein, hFc Tag

Name: Human PRND Protein, hFc Tag
Brand: KMD Bioscience
SKU: KMP3187

KMP3187

朊病毒样蛋白双倍体, Human PRND Protein, hFc Tag, PRND

DATASHEET MSDS

Product Description

Alias	朊病毒样蛋白双倍体, Human PRND Protein, hFc Tag, PRND
Catalog Number	KMP3187
Product Description	The Human PRND Protein(KMP3187) is produced in HEK293 Cells. The target gene encoding the human PRND (NP_036541.2) (Met1-Gly152) is expressed with the Fc region of human IgG1 at the C-terminus.
Molecular Name	PRND
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	Doppel (PRND) is a paralogue of the mammalian prion (PRNP) gene. It is abundant in testis and, unlike PRNP, it is expressed at low levels in the adult central nervous system (CNS). Besides, doppel overexpression correlates with some prion-disease pathological features, such as ataxia and death of cerebellar neurons. Prion-related protein doppel gene (PRND), as an essential member of the mammalian prion gene family, is associated with the scrapie susceptibility as well as phenotype traits, so the genetic variation of the PRND has been highly concerned recently, including the single nucleiotide polymorphism (SNP) and insertion/deletion (indel).
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	41.2 kDa

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