Home
>>
Products
>>
Proteins
>>
Recombinant Proteins
>
Human CD45 Protein, His Tag

Human CD45 Protein, His Tag

Product Number

KMP3141

Alias

白细胞共同抗原, Human CD45 Protein, His Tag, CD45

Specifications
  • 50ug
  • 100ug
  • 200ug
Product Description
Alias白细胞共同抗原, Human CD45 Protein, His Tag, CD45
Catalog NumberKMP3141
Product DescriptionThe Human CD45 Protein(KMP3141) is produced in HEK293 Cells. The target gene encoding the human CD45 (NP_002829.3) (Gln26-Lys575) is expressed with a polyhistidine tag at the C-terminus.
Molecular NameCD45
SpeciesHuman
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundThe cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behAvior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Protein tyrosine phosphatase, receptor type C (CD45), also known as PTPRC is a member of the protein tyrosine phosphatase (PTP) family which is known for its function to serve as signaling molecules and to regulate a variety of cellular processes such as cell proliferation, differentiation, mitotic cycle and oncogenic transformation. CD45 is found expression specifically in hemotopietic cells. CD45 consists of an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains. It serves as an essential regulator of T-cell and B-cell antigen receptor signaling through either direct interaction with components of the antigen receptor complexes or by activating various Src family kinases required for the antigen receptor signaling and it also can suppress JAK kinases.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight62.2 kDa

Login

Don’t have an account?Sign Up Now

Register

Already have an account?Log In Now

Inquire Now