Human ILT4 Protein, His Tag
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Product Number
KMP3135
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Alias
白细胞免疫球蛋白样受体B2, Human ILT4 Protein, His Tag, ILT4
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Specifications
- 50ug
- 100ug
- 200ug
Product Description
| Alias | 白细胞免疫球蛋白样受体B2, Human ILT4 Protein, His Tag, ILT4 |
| Catalog Number | KMP3135 |
| Product Description | The Human ILT4 Protein(KMP3135) is produced in HEK293 Cells. The target gene encoding the human LILRB2 (AAH36827.1) (Met1-Val461) is expressed with a C-terminal polyhistidine tag. The purified protein is biotinylated in vitro. |
| Molecular Name | ILT4 |
| Species | Human |
| Host | HEK293 Cells |
| Size | 50ug, 100ug, 200ug |
| Purity | >90% as determined by SDS-PAGE |
| Purification | Affinity purification |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Formulation | PBS, pH7.4 |
| Background | ILT4, also known as LILRB2, is a member of the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). ILT4 gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family. Multiple transcript variants encoding different isoforms have been found for the ILT4 gene. ILT4 is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
| Molecular Weight | 49.2 kDa |
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