Human LCAT Protein, His Tag
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Product Number
KMP3054
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Alias
卵磷脂胆固醇酰基转移酶, Human LCAT Protein, His Tag, LCAT
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Specifications
- 50ug
- 100ug
- 200ug
Product Description
| Alias | 卵磷脂胆固醇酰基转移酶, Human LCAT Protein, His Tag, LCAT |
| Catalog Number | KMP3054 |
| Product Description | The Human LCAT Protein(KMP3054) is produced in HEK293 Cells. The target gene encoding the human LCAT (NP_000220.1) (Met1-Glu440) is expressed with a polyhistidine tag at the C-terminus. |
| Molecular Name | LCAT |
| Species | Human |
| Host | HEK293 Cells |
| Size | 50ug, 100ug, 200ug |
| Purity | >85% as determined by SDS-PAGE |
| Purification | Affinity purification |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Formulation | PBS, pH7.4 |
| Background | Lecithin: cholesterol acyltransferase (LCAT) is the sole enzyme that esterifies cholesterol in plasma, thus determining the maturation of high-density lipoproteins. Because it maintains an unesterified cholesterol gradient between peripheral cells and extracellular acceptors, for a long time, LCAT has been considered as a key enzyme in reverse cholesterol transport. Lecithin cholesterol acyltransferase (LCAT) plays a pivotal role in HDL metabolism.LCAT is intimately involved in HDL maturation and is a key component of the reverse cholesterol transport (RCT) pathway which removes excess cholesterol molecules from the peripheral tissues to the liver for excretion. LCAT may also modify oxidative and inflammatory processes, as supported by an inverse relationship with HDL antioxidative functionality and a positive relationship with high-sensitivity C-reactive protein (hsCRP). |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
| Molecular Weight | 48.5 kDa |
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