Human PRNP Protein, hFc Tag

Name: Human PRNP Protein, hFc Tag
Brand: KMD Bioscience
SKU: KMP2973

KMP2973

朊蛋白, Human PRNP Protein, hFc Tag, PRNP

DATASHEET MSDS

Product Description

Alias	朊蛋白, Human PRNP Protein, hFc Tag, PRNP
Catalog Number	KMP2973
Product Description	The Human PRNP Protein(KMP2973) is produced in HEK293 Cells. The target gene encoding the human PRNP (NP_000302.1) (Met1-Gly229) is expressed with the Fc region of human IgG1 at the C-terminus.
Molecular Name	PRNP
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>90% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	Prion protein (PRNP) gene is well known for affecting mammal transmissible spongiform encephalopathies (TSE), and is also reported to regulate phenotypic traits (e.g. growth traits) in healthy ruminants. PRNP is fundamental in the pathogenesis of transmissible spongiform encephalopathies. Generally, PRNP gene is associated with prion diseases, whereas variants of the PRNP gene may also explain some cases of Alzheimer disease (AD) and frontotemporal dementia (FTD) in Caucasian populations.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	49.7 kDa

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