Human IL17 Protein, His Tag

Name: Human IL17 Protein, His Tag
Brand: KMD Bioscience
SKU: KMP2970

Product Number

KMP2970

Alias

白细胞介素 17, Human IL17 Protein, His Tag, IL17

Specifications

50ug
100ug
200ug

DATASHEET MSDS

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Product Description

Alias	白细胞介素 17, Human IL17 Protein, His Tag, IL17
Catalog Number	KMP2970
Product Description	The Human IL17 Protein(KMP2970) is produced in Insect Cells. The target gene encoding the mature form of human IL17A (Q16552, with mutation Thr 26 Ala) (Gly24-Ala155) is expressed with a polyhistidine tag at the N-terminus.
Molecular Name	IL17
Species	Human
Host	Insect Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	20mM PB, 500mM NaCl, 10% Glycerol, pH7.0
Background	IL17, also known as IL17a, is a cytokine that belongs to the IL-17 family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proliferation, differentiation, and cell survival/apoptosis but are also involved in several pathophysiological processes including viral infections and autoimmune diseases. Cytokines are synthesized under various stimuli by a variety of cells of both the innate (monocytes, macrophages, dendritic cells) and adaptive (T- and B-cells) immune systems. The IL-17 family of cytokines includes six members, IL-17/IL-17A, IL-17B, IL-17C, IL-17D, IL-17E/IL-25, and IL-17F, which are produced by multiple cell types. IL-17 regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis, and multiple sclerosis.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	17.2 kDa

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Human IL17 Protein, His Tag

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