Home
>>
Products
>>
Proteins
>>
Recombinant Proteins
>
Human Clusterin Protein, His Tag

Human Clusterin Protein, His Tag

Product Number

KMP2882

Alias

丛生蛋白, Human Clusterin Protein, His Tag, Clusterin

Specifications
  • 50ug
  • 100ug
  • 200ug
Product Description
Alias丛生蛋白, Human Clusterin Protein, His Tag, Clusterin
Catalog NumberKMP2882
Product DescriptionThe Human Clusterin Protein(KMP2882) is produced in HEK293 Cells. The target gene encoding the Human CLU (NP_001822.3) (Met1-Glu449) is expressed with a polyhistidine tag at the C-terminus.
Molecular NameClusterin
SpeciesHuman
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundClusterin, also known as complement-associated protein SP-40, Complement cytolysis inhibitor, Apolipoprotein J, Testosterone-repressed prostate message 2, Aging-associated gene 4 protein, CLU and APOJ, is a secreted protein which belongs to the clusterin family. Clusterin/Apolipoprotein J/Apo-J is an enigmatic glycoprotein with a nearly ubiquitous tissue distribution and an apparent involvement in biological processes ranging from mammary gland involution to neurodegeneration in Alzheimer's disease. Its major form, a heterodimer, is secreted and present in physiological fluids, but truncated forms targeted to the nucleus have also been identified. Clusterin/Apolipoprotein J/Apo-J is a widely distributed glycoprotein with a wide range of biologic properties. A prominent and defining feature of clusterin is its marked induction in such disease states as glomerulonephritis, cystic renal disease, renal tubular injury, neurodegenerative conditions, atherosclerosis, and myocardial infarction. Upregulation of clusterin mRNA and protein levels detected in diverse disease states and in in vitro systems have led to suggestions that it functions in membrane lipid recycling, in apoptotic cell death, and as a stress-induced secreted chaperone protein, amongst others.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight51.51 kDa

Login

Don’t have an account?Sign Up Now

Register

Already have an account?Log In Now

Inquire Now