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Rabbit Anti-Human ACTN4 pAb

Rabbit Anti-Human ACTN4 pAb

Product Number

PA9996

Alias

ACTN4, ACTININ-4, FSGS, FSGS1

Specifications
  • 50ul
  • 100ul
Product Description
AliasACTN4, ACTININ-4, FSGS, FSGS1
Catalog NumberPA9996
Molecular NameACTN4
HostRabbit
Size50ul, 100ul
ClonityPolyclonal
PurificationAffinity Purification
FormulationSupply in PBS with 0.02% sodium azide, 50% glycerol, pH 7.4.
ImmunogenRecombinant fusion protein containing a sequence corresponding to a.a. 570-650 of human ACTN4 (NP_004915.2).
ApplicationWB, IF
Storage ConditionStore the product under sterile conditions after opening at -20℃. Avoid freeze-thaw cycles.
Shipping ConditionShipped on ice packs.
Product Declaration本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。
Product Full NameRabbit Anti-Human ACTN4 Polyclonal Antibody
FAQ
  • Q1- ACTN4的生物学意义是什么?

    ACTN4(α-Actinin 4)调控肌动蛋白交联,与细胞迁移和癌症转移相关,其突变导致家族性局灶节段性肾小球硬化(FSGS)。

  • Q2- 是否适用于肾活检样本的IHC检测?

    是的,已验证FSGS患者肾组织石蜡切片,抗体稀释1:200。

  • Q3- 抗体是否识别磷酸化ACTN4(如Tyr265)?

    不识别,本抗体针对总蛋白,需搭配磷酸化抗体研究修饰状态。

  • Q4- 是否提供癌症转移模型的验证数据?

    是的,提供卵巢癌细胞中ACTN4过表达与侵袭性增强的相关数据。

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