SLC7A11的分子功能是什么？

SLC7A11（xCT）介导胱氨酸/谷氨酸交换，调控氧化应激防御及铁死亡抵抗，其过表达与癌症化疗耐药相关。

是否适用于铁死亡研究？

可以，推荐使用Erastin或RSL3处理模型，检测脂质ROS水平及细胞存活率变化。

经测试无交叉反应，特异性针对SLC7A11。

PA7298

SLC7A11, CCBR1, xCT

DATASHEET MSDS

Product Description

Alias	SLC7A11, CCBR1, xCT
Catalog Number	PA7298
Molecular Name	SLC7A11
Host	Rabbit
Size	50ul, 100ul
Clonity	Polyclonal
Purification	Affinity Purification
Formulation	Supply in PBS with 0.02% sodium azide, 50% glycerol, pH 7.4.
Immunogen	A synthetic peptide corresponding to a sequence within a.a. 150-250 of human SLC7A11 (NP_055146.1).
Application	WB
Storage Condition	Store the product under sterile conditions after opening at -20℃. Avoid freeze-thaw cycles.
Shipping Condition	Shipped on ice packs.
Product Declaration	本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。
Product Full Name	Rabbit Anti-Human SLC7A11 Polyclonal Antibody

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