Rabbit Anti-Human BFAR pAb
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Product Number
PA16455
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Alias
BFAR, BAR, RNF47
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Specifications
- 50ul
- 100ul
Product Description
| Alias | BFAR, BAR, RNF47 |
| Catalog Number | PA16455 |
| Molecular Name | BFAR |
| Host | Rabbit |
| Size | 50ul, 100ul |
| Clonity | Polyclonal |
| Purification | Affinity Purification |
| Formulation | Supply in PBS with 0.02% sodium azide, 50% glycerol, pH 7.4. |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to a.a. 1-140 of human BFAR (NP_057645.1). |
| Application | WB, IF |
| Storage Condition | Store the product under sterile conditions after opening at -20℃. Avoid freeze-thaw cycles. |
| Shipping Condition | Shipped on ice packs. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human BFAR Polyclonal Antibody |
FAQ
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Q1-BFAR的生物学功能是什么？
BFAR（双功能凋亡调节因子）调控内质网应激诱导的凋亡，通过结合TRAF2抑制Caspase-8激活，其异常与肝癌及神经退行相关。
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Q2-是否适用于内质网应激模型？
可以，推荐使用衣霉素处理的肝细胞，通过WB检测BFAR与TRAF2的互作及CHOP表达上调。
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Q3-是否与Bcl-2家族交叉反应？
经测试无交叉反应，特异性针对BFAR。
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