BRCA2的分子功能是什么？

BRCA2是DNA同源重组修复关键因子，其胚系突变导致遗传性乳腺癌/卵巢癌综合征（HBOC），并影响PARP抑制剂疗效。

是否适用于PARP抑制剂耐药研究？

可以，推荐使用BRCA2缺失细胞，通过彗星实验检测DNA损伤累积。

经测试无交叉反应，特异性针对BRCA2。

PA12919

BRCA2, BRCC2, BROVCA2, FACD, FAD, FAD1, FANCD, FANCD1, GLM3, PNCA2, XRCC11

DATASHEET MSDS

Product Description

Alias	BRCA2, BRCC2, BROVCA2, FACD, FAD, FAD1, FANCD, FANCD1, GLM3, PNCA2, XRCC11
Catalog Number	PA12919
Molecular Name	BRCA2
Host	Rabbit
Size	50ul, 100ul
Clonity	Polyclonal
Purification	Affinity Purification
Formulation	Supply in PBS with 0.02% sodium azide, 50% glycerol, pH 7.4.
Immunogen	Recombinant fusion protein containing a sequence corresponding to a.a. 1-300 of human BRCA2 (NP_000050.2).
Application	WB, IF
Storage Condition	Store the product under sterile conditions after opening at -20℃. Avoid freeze-thaw cycles.
Shipping Condition	Shipped on ice packs.
Product Declaration	本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。
Product Full Name	Rabbit Anti-Human BRCA2 Polyclonal Antibody

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