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Rabbit Anti-Human ACVRL1 Polyclonal Antibody

Rabbit Anti-Human ACVRL1 Polyclonal Antibody

Product Number

PA11341

Alias

ACVRL1, ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, TSR-I

Specifications
  • 50ul
  • 100ul
Product Description
AliasACVRL1, ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, TSR-I
Catalog NumberPA11341
Molecular NameACVRL1
HostRabbit
Size50ul, 100ul
ClonityPolyclonal
PurificationAffinity Purification
FormulationSupply in PBS with 0.02% sodium azide, 50% glycerol, pH 7.4.
ImmunogenRecombinant protein of human ACVRL1
ApplicationWB
Storage ConditionStore the product under sterile conditions after opening at -20℃. Avoid freeze-thaw cycles.
Shipping ConditionShipped on ice packs.
Product Declaration本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。
FAQ
  • Q1- ACVRL1(ALK1)的生物学意义是什么?

    ACVRL1是TGF-β/BMP受体,其突变导致遗传性出血性毛细血管扩张症(HHT),表现为血管畸形和反复出血。

  • Q2- 是否适用于血管组织的免疫组化(IHC)?

    是的,推荐石蜡切片,需EDTA抗原修复(pH 9.0,高压20分钟),抗体稀释1:200。

  • Q3- WB中预期条带大小?

    理论分子量约55 kDa,实际可能因糖基化显示为60-65 kDa。

  • Q4- 是否识别小鼠Acvrl1蛋白?

    与人ACVRL1同源性约85%,可交叉检测,推荐WB起始稀释1:800。

  • Q5- 是否提供HHT患者样本验证数据?

    是的,提供HHT患者皮肤血管畸形组织的IHC显示ACVRL1表达缺失的结果。

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