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Recombinant Human anti-COVID-19/SARS-CoV-2 S2 Protein Monoclonal Antibody

Recombinant Human anti-COVID-19/SARS-CoV-2 S2 Protein Monoclonal Antibody

Product Number

MAV108

Alias

SARS-CoV-2 S1-S2 Protein antibody, 2019-nCoV, Coronavirus, N protein antibody

Specifications
  • 100ul
  • 500ul
Product Description
AliasSARS-CoV-2 S1-S2 Protein antibody, 2019-nCoV, Coronavirus, N protein antibody
Catalog NumberMAV108
Product DescriptionThe product is specific for SARS-CoV-2 S1-S2 protein subunit(Cat.#: COV366).
Molecular NameCOVID-19
SpeciesCOVID-19
HostHuman
Size100ul, 500ul
ClonityRecombinant mAb
Clone Number6B9
Concentration1mg/ml
Antibody IsotypeIgG1
Formulation0.01M PBS, pH 7.4
BackgroundThe spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell: they are essential for both host specificity and viral infectivity. The term 'peplomer' is typically used to refer to a grouping of heterologous proteins on the virus surface that function together. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. The SARS-CoV spike (S) protein is composed of two subunits; the S1 subunit contains a receptor-binding domain that engages with the host cell receptor angiotensin-converting enzyme 2 and the S2 subunit mediates fusion between the viral and host cell membranes. The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity, during infection with SARS-CoV.
ImmunogenNative virus
ApplicationELISA, Native Virus Detection
Biological ActivityN.A
Cross-reactivityReact with SARS-CoV-2(COVID-19) S1-S2 protein. Do not react with other SARS-CoV-2 subunits.
Storage ConditionThis product can be stored at 2℃-8℃ for one month. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles.
Product DeclarationThis product is for research use only and must not be used directly on humans or for injection.

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