Recombinant Human anti-COVID-19/SARS-CoV-2 NTD Protein Monoclonal Antibody_KMD Bioscience

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Recombinant Human anti-COVID-19/SARS-CoV-2 NTD Protein Monoclonal Antibody

Recombinant Human anti-COVID-19/SARS-CoV-2 NTD Protein Monoclonal Antibody

Product Number

MAV104

Alias

SARS-CoV-2 S1 NTD domain protein antibody, 2019-nCoV, Coronavirus

Specifications

100ul
500ul

DATASHEET MSDS

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Product Description

Alias	SARS-CoV-2 S1 NTD domain protein antibody, 2019-nCoV, Coronavirus
Catalog Number	MAV104
Product Description	The product is specific for SARS-CoV-2 Spike Protein S1 NTD domain(Cat.#: COV365). Cat#. MAV104 and Cat#.MAV105 are antibody pair which is verified for ELISA.
Molecular Name	COVID-19
Species	COVID-19
Host	Human
Size	100ul, 500ul
Clonity	Recombinant mAb
Clone Number	6F8
Concentration	1mg/ml
Antibody Isotype	IgG1
Formulation	0.01M PBS, pH 7.4
Background	The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell: they are essential for both host specificity and viral infectivity. The term 'peplomer' is typically used to refer to a grouping of heterologous proteins on the virus surface that function together. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. The SARS-CoV spike (S) protein is composed of two subunits; the S1 subunit contains a receptor-binding domain that engages with the host cell receptor angiotensin-converting enzyme 2 and the S2 subunit mediates fusion between the viral and host cell membranes. The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity, during infection with SARS-CoV.
Immunogen	Native virus
Application	ELISA
Biological Activity	IC50 = 112 ng/mL using using ELISA method
Cross-reactivity	React with SARS-CoV-2(COVID-19) S1-NTD protein. Do not react with other SARS-CoV-2 subunits.
Storage Condition	This product can be stored at 2℃-8℃ for one month. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles.
Product Declaration	This product is for research use only and must not be used directly on humans or for injection.

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