Rabbit Anti-Human ATG16L1 pAb
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Product Number
PA5700
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Alias
ATG16L1, APG16L, ATG16A, ATG16L, IBD10, WDR30
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Specifications
- 50ul
- 100ul
Product Description
| Alias | ATG16L1, APG16L, ATG16A, ATG16L, IBD10, WDR30 |
| Catalog Number | PA5700 |
| Molecular Name | ATG16L1 |
| Host | Rabbit |
| Size | 50ul, 100ul |
| Clonity | Polyclonal |
| Purification | Affinity Purification |
| Formulation | Supply in PBS with 0.02% sodium azide, 50% glycerol, pH 7.4. |
| Immunogen | A synthetic peptide corresponding to a sequence within a.a. 200-300 of human ATG16L1 (NP_110430.5). |
| Application | WB, IF |
| Storage Condition | Store the product under sterile conditions after opening at -20℃. Avoid freeze-thaw cycles. |
| Shipping Condition | Shipped on ice packs. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human ATG16L1 Polyclonal Antibody |
FAQ
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Q1-ATG16L1的生物学功能是什么？
ATG16L1是自噬体膜延伸的关键蛋白，与ATG5-ATG12复合体结合，调控LC3脂化及自噬体形成，其突变与克罗恩病（Crohn's disease）风险相关。
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Q2-是否适用于炎症性肠病模型研究？
可以，推荐使用ATG16L1敲除小鼠肠道组织，通过IHC检测潘氏细胞异常及自噬缺陷。
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Q3-是否与ATG16L2交叉反应？
经测试无交叉反应，特异性针对ATG16L1。
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