Rabbit Anti-Human BECN1 pAb
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Product Number
PA5634
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Alias
ATG6, VPS30, beclin1, Beclin 1, BECN1, beclin-1
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Specifications
- 50ul
- 100ul
Product Description
| Alias | ATG6, VPS30, beclin1, Beclin 1, BECN1, beclin-1 |
| Catalog Number | PA5634 |
| Molecular Name | BECN1 |
| Host | Rabbit |
| Size | 50ul, 100ul |
| Clonity | Polyclonal |
| Purification | Affinity Purification |
| Formulation | Supply in PBS with 0.02% sodium azide, 50% glycerol, pH 7.4. |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to a.a. 1-280 of human Beclin 1 (NP_003757.1). |
| Application | WB |
| Storage Condition | Store the product under sterile conditions after opening at -20℃. Avoid freeze-thaw cycles. |
| Shipping Condition | Shipped on ice packs. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human BECN1 Polyclonal Antibody |
FAQ
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Q1-BECN1的分子功能是什么？
BECN1（Beclin 1）是自噬核心蛋白，通过结合PI3K复合体调控自噬体形成，其缺失导致自噬缺陷及肿瘤发生风险增加。
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Q2-是否适用于自噬流检测？
可以，推荐使用雷帕霉素或饥饿处理的细胞，通过WB检测LC3-II/LC3-I比值变化及SQSTM1/p62降解。
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Q3-是否与BECN2交叉反应？
经测试无交叉反应，特异性针对BECN1。
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