SIN3B的生物学作用是什么？

SIN3B是组蛋白去乙酰化酶复合体（HDAC）核心组件，调控基因沉默及细胞周期退出，其缺失导致癌症转移和化疗耐药。

是否适用于表观遗传研究？

可以，推荐使用ChIP-seq检测SIN3B结合的启动子区域及组蛋白H3K9乙酰化水平变化。

经测试无交叉反应，特异性针对SIN3B。

PA5174

SIN3B

DATASHEET MSDS

Product Description

Alias	SIN3B
Catalog Number	PA5174
Molecular Name	SIN3B
Host	Rabbit
Size	50ul, 100ul
Clonity	Polyclonal
Purification	Affinity Purification
Formulation	Supply in PBS with 0.02% sodium azide, 50% glycerol, pH 7.4.
Immunogen	Recombinant fusion protein containing a sequence corresponding to a.a. 1-160 of human SIN3B (NP_056075.1).
Application	WB
Storage Condition	Store the product under sterile conditions after opening at -20℃. Avoid freeze-thaw cycles.
Shipping Condition	Shipped on ice packs.
Product Declaration	本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。
Product Full Name	Rabbit Anti-Human SIN3B Polyclonal Antibody

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