ATP4B的生物学功能是什么？

ATP4B是胃质子泵（H⁺/K⁺-ATP酶）β亚基，与ATP4A共同介导胃酸分泌，其异常与胃溃疡及反流性食管炎相关。

是否适用于胃酸抑制药物研究？

可以，推荐使用奥美拉唑处理的胃壁细胞，通过IHC检测ATP4B表达变化。

经测试无交叉反应，特异性针对ATP4B。

PA4705

ATP4B, ATP6B

DATASHEET MSDS

Product Description

Alias	ATP4B, ATP6B
Catalog Number	PA4705
Molecular Name	ATP4B
Host	Rabbit
Size	50ul, 100ul
Clonity	Polyclonal
Purification	Affinity Purification
Formulation	Supply in PBS with 0.02% sodium azide, 50% glycerol, pH 7.4.
Immunogen	Recombinant fusion protein containing a sequence corresponding to a.a. 62-291 of human ATP4B (NP_000696.1).
Application	WB, IHC
Storage Condition	Store the product under sterile conditions after opening at -20℃. Avoid freeze-thaw cycles.
Shipping Condition	Shipped on ice packs.
Product Declaration	本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。
Product Full Name	Rabbit Anti-Human ATP4B Polyclonal Antibody

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