Rabbit anti-COVID-19/SARS-CoV-2 S Protein Polyclonal Antibody
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Product Number
PAV201
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Alias
SARS-CoV-2 spike glycoprotein; SARS-CoV-2 spike; SARS-CoV-2; SARS-CoV; 2019-nCoV; Coronavirus
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Specifications
- 100ul
- 500ul
Product Description
| Alias | SARS-CoV-2 spike glycoprotein; SARS-CoV-2 spike; SARS-CoV-2; SARS-CoV; 2019-nCoV; Coronavirus |
| Catalog Number | PAV201 |
| Product Description | This product is generated by immuning rabbits with recombinant SARS-CoV-2 S1 protein (Cat.#: COV362)and purified with Protein A/G, which is specific for native SARS-CoV-2 detection. |
| Molecular Name | COVID-19 |
| Species | COVID-19 |
| Host | Rabbit |
| Size | 100ul, 500ul |
| Clonity | Polyclonal |
| Concentration | 1mg/ml |
| Antibody Isotype | N.A |
| Formulation | 0.01M PBS, pH 7.4 |
| Background | The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell: they are essential for both host specificity and viral infectivity. The term 'peplomer' is typically used to refer to a grouping of heterologous proteins on the virus surface that function together. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. The SARS-CoV spike (S) protein is composed of two subunits; the S1 subunit contains a receptor-binding domain that engages with the host cell receptor angiotensin-converting enzyme 2 and the S2 subunit mediates fusion between the viral and host cell membranes. The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity, during infection with SARS-CoV. |
| Immunogen | Recombinant SARS-CoV-2 S1 protein(Cat.#: COV362) |
| Application | ELISA |
| Biological Activity | N.A |
| Cross-reactivity | React with SARS-CoV-2(COVID-19) S1 protein. Do not react with other SARS-CoV-2 subunits. |
| Storage Condition | This product can be stored at 2℃-8℃ for one month. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
| Product Declaration | This product is for research use only and must not be used directly on humans or for injection. |
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