SIGLEC12的生物学意义是什么？

SIGLEC12是巨噬细胞抑制性受体，其基因多态性与炎症性肠病（IBD）及结直肠癌风险相关。

是否适用于肠道炎症研究？

可以，推荐使用DSS诱导的结肠炎小鼠，检测结肠组织损伤及巨噬细胞极化（M1/M2）失衡。

分装后-20℃保存，WB建议1:1000，IF建议1:200，有效期2年。

PA16656

SIGLEC12, S2V, SIGLECL1, SLG, Siglec-XII

DATASHEET MSDS

Product Description

Alias	SIGLEC12, S2V, SIGLECL1, SLG, Siglec-XII
Catalog Number	PA16656
Molecular Name	SIGLEC12
Host	Rabbit
Size	50ul, 100ul
Clonity	Polyclonal
Purification	Affinity Purification
Formulation	Supply in PBS with 0.02% sodium azide, 50% glycerol, pH 7.4.
Immunogen	Recombinant fusion protein containing a sequence corresponding to a.a. 20-210 of human SIGLEC12 (NP_443729.1).
Application	WB
Storage Condition	Store the product under sterile conditions after opening at -20℃. Avoid freeze-thaw cycles.
Shipping Condition	Shipped on ice packs.
Product Declaration	本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。
Product Full Name	Rabbit Anti-Human SIGLEC12 Polyclonal Antibody

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