Rabbit Anti-Human ASPA pAb
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Product Number
PA15554
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Alias
ASPA, ACY2, ASP
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Specifications
- 50ul
- 100ul
Product Description
| Alias | ASPA, ACY2, ASP |
| Catalog Number | PA15554 |
| Molecular Name | ASPA |
| Host | Rabbit |
| Size | 50ul, 100ul |
| Clonity | Polyclonal |
| Purification | Affinity Purification |
| Formulation | Supply in PBS with 0.02% sodium azide, 50% glycerol, pH 7.4. |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to a.a. 1-313 of human ASPA (NP_001121557.1). |
| Application | WB, IF |
| Storage Condition | Store the product under sterile conditions after opening at -20℃. Avoid freeze-thaw cycles. |
| Shipping Condition | Shipped on ice packs. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human ASPA Polyclonal Antibody |
FAQ
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Q1-ASPA的生物学功能是什么？
ASPA（天冬氨酸酰化酶）催化神经代谢物N-乙酰天冬氨酸（NAA）水解为天冬氨酸和乙酸，对中枢神经系统髓鞘的形成和维持至关重要。其活性缺失会导致NAA积累，引发卡纳万病（Canavan disease），一种致命性脑白质营养不良症。
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Q2-是否适用于卡纳万病或髓鞘相关研究？
可以，推荐使用卡纳万病患者脑组织或ASPA敲除动物模型，通过WB或IHC检测ASPA表达缺失及NAA水平升高。
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Q3-是否与其他酰化酶（如ACOX1）交叉反应？
经测试无交叉反应，特异性针对人源ASPA，不识别其他代谢酶类。
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Q4-Western Blot中如何优化脑组织样本处理？
使用含1% Triton X-100的裂解液提取脑组织蛋白，避免过度超声以减少髓鞘脂蛋白干扰。
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Q5-保存条件及稀释建议？
分装后-20℃保存，避免反复冻融；WB建议1:1000稀释，IHC建议1:200，有效期2年。
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- E-mail：[email protected]
- Address：Room 108, Building 10, No. 6 Hechang Road, Wuqing Development Zone, Tianjin City
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