Rabbit Anti-Human BRD4 pAb
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Product Number
PA12884
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Alias
BRD4, CAP, HUNK1, HUNKI, MCAP
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Specifications
- 50ul
- 100ul
Product Description
| Alias | BRD4, CAP, HUNK1, HUNKI, MCAP |
| Catalog Number | PA12884 |
| Molecular Name | BRD4 |
| Host | Rabbit |
| Size | 50ul, 100ul |
| Clonity | Polyclonal |
| Purification | Affinity Purification |
| Formulation | Supply in PBS with 0.02% sodium azide, 50% glycerol, pH 7.4. |
| Immunogen | A synthetic peptide corresponding to a sequence within a.a. 1100-1200 of human BRD4 (NP_490597.1). |
| Application | WB, IHC, IF |
| Storage Condition | Store the product under sterile conditions after opening at -20℃. Avoid freeze-thaw cycles. |
| Shipping Condition | Shipped on ice packs. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human BRD4 Polyclonal Antibody |
FAQ
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Q1-BRD4的生物学意义是什么？
BRD4（含溴结构域蛋白4）是BET蛋白家族成员，通过结合乙酰化组蛋白驱动致癌基因（如MYC）转录，其异常表达与白血病、肺癌及靶向治疗耐药相关。
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Q2-是否适用于BET抑制剂研究？
可以，推荐使用JQ1或OTX015处理的癌细胞，通过qPCR检测MYC表达下调及凋亡率升高。
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Q3-是否与BRD2或BRD3交叉反应？
经测试无交叉反应，特异性针对BRD4。
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