ATP2B1的生物学意义是什么？

ATP2B1（质膜钙泵PMCA1）调控细胞内钙稳态，其突变导致听力丧失及神经退行性。

是否适用于耳蜗或神经元模型？

可以，推荐使用耳蜗毛细胞或原代神经元，通过IF检测ATP2B1在质膜的定位。

使用含1% Triton X-100的裂解液，添加蛋白酶抑制剂混合物。

PA12104

DATASHEET MSDS

Product Description

Catalog Number	PA12104
Molecular Name	ATP2B1
Host	Rabbit
Size	50ul, 100ul
Clonity	Polyclonal
Purification	Affinity Purification
Formulation	Supply in PBS with 0.02% sodium azide, 50% glycerol, pH 7.4.
Immunogen	A synthetic peptide corresponding to a sequence within a.a. 250-350 of human ATP2B1 (NP_001673.2).
Application	WB
Storage Condition	Store the product under sterile conditions after opening at -20℃. Avoid freeze-thaw cycles.
Shipping Condition	Shipped on ice packs.
Product Declaration	本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。

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