Rabbit Anti-human BBC3 pAb
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Product Number
PA10730
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Alias
BBC3, JFY-1, JFY1, PUMA
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Specifications
- 50ul
- 100ul
Product Description
| Alias | BBC3, JFY-1, JFY1, PUMA |
| Catalog Number | PA10730 |
| Molecular Name | BBC3 |
| Host | Rabbit |
| Size | 50ul, 100ul |
| Clonity | Polyclonal |
| Purification | Affinity Purification |
| Formulation | Supply in PBS with 0.02% sodium azide, 50% glycerol, pH 7.4. |
| Immunogen | A synthetic peptide corresponding to a sequence within a.a. 50 to the C-terminus of human BBC3 (NP_001120713.1). |
| Application | WB, IHC, IF |
| Storage Condition | Store the product under sterile conditions after opening at -20℃. Avoid freeze-thaw cycles. |
| Shipping Condition | Shipped on ice packs. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-human BBC3 Polyclonal Antibody |
FAQ
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Q1-BBC3的生物学意义是什么？
BBC3（PUMA）是p53下游促凋亡蛋白，其激活导致线粒体凋亡通路活化，其缺失与癌症化疗抵抗相关。
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Q2-是否适用于DNA损伤模型？
可以，推荐使用顺铂处理的癌细胞，通过WB检测PUMA与BAX的共激活。
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Q3-是否与NOXA交叉反应？
经测试无交叉反应，特异性针对BBC3（PUMA）。
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