Rabbit Anti-Human BAG3 pAb
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Product Number
PA8449
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Alias
BAG3, BAG-3, BIS, CAIR-1, MFM6
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Specifications
- 50ul
- 100ul
Product Description
| Alias | BAG3, BAG-3, BIS, CAIR-1, MFM6 |
| Catalog Number | PA8449 |
| Molecular Name | BAG3 |
| Host | Rabbit |
| Size | 50ul, 100ul |
| Clonity | Polyclonal |
| Purification | Affinity Purification |
| Formulation | Supply in PBS with 0.02% sodium azide, 50% glycerol, pH 7.4. |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to a.a. 380-575 of human BAG3 (NP_004272.2). |
| Application | WB, IHC, IF, IP |
| Storage Condition | Store the product under sterile conditions after opening at -20℃. Avoid freeze-thaw cycles. |
| Shipping Condition | Shipped on ice packs. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human BAG3 Polyclonal Antibody |
FAQ
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Q1-BAG3的生物学功能是什么？
BAG3（Bcl-2-associated athanogene 3）通过结合Hsp70调控自噬及错误折叠蛋白清除，其突变导致肌萎缩侧索硬化症（ALS）及心肌病。
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Q2-是否适用于神经退行或心脏模型？
可以，推荐使用ALS患者iPSC分化的运动神经元，通过IF检测BAG3与泛素化蛋白聚集体的共定位。
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Q3-是否与BAG1交叉反应？
经测试无交叉反应，特异性针对BAG3。
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