Host defense/stress proteins are a protein system that rapidly responds and exerts protective functions when the body faces infection, injury, or environmental stress. These proteins are widely involved in key processes such as pathogen recognition and clearance, inflammatory regulation, tissue repair, and oxidative stress defense, constituting an important component of the body's innate immune system. Through various mechanisms such as directly killing pathogens, opsonizing phagocytosis, neutralizing toxins, and regulating immune cell activity, they collaboratively defend against external threats; their expression levels are usually significantly upregulated under stress conditions, making them important molecular indicators reflecting the body's immune status and inflammation level.

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